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One True Thing
Anna Quindlen, 1994
Random House
320 pp.
ISBN-13: 9780812976182

Summary
A young woman returns home from New York to care for her dying mother.  In the process she comes to appreciate the choices her mother made in her own life. (From the publisher.)

The book was adapted to film in 1999 with Meryl Streep and Renee Zellweger.